Sofosbuvir, a novel nucleotide analogue inhibitor used for the treatment of hepatitis <fc>C</fc> virus
![Viruses | Free Full-Text | Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations Viruses | Free Full-Text | Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations](https://pub.mdpi-res.com/viruses/viruses-08-00283/article_deploy/html/images/viruses-08-00283-g002.png?1477893030)
Viruses | Free Full-Text | Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations
![Telaprevir Alone or With Peginterferon and Ribavirin Reduces HCV RNA in Patients With Chronic... - YouTube Telaprevir Alone or With Peginterferon and Ribavirin Reduces HCV RNA in Patients With Chronic... - YouTube](https://i.ytimg.com/vi/K9OY39bMprk/hq720.jpg?sqp=-oaymwEhCK4FEIIDSFryq4qpAxMIARUAAAAAGAElAADIQj0AgKJD&rs=AOn4CLCyPaL38uIRppLXIjho5m2xG2avJA)
Telaprevir Alone or With Peginterferon and Ribavirin Reduces HCV RNA in Patients With Chronic... - YouTube
![Core Concepts - Extrahepatic Conditions Related to HCV infection - Evaluation, Staging, and Monitoring of Chronic Hepatitis C - Hepatitis C Online Core Concepts - Extrahepatic Conditions Related to HCV infection - Evaluation, Staging, and Monitoring of Chronic Hepatitis C - Hepatitis C Online](https://cdn.hepatitisc.uw.edu/doc/483-1/major-pathophysiological-mechanisms-implicated-extrahepatic-manifestations-hcv-infection.jpg)
Core Concepts - Extrahepatic Conditions Related to HCV infection - Evaluation, Staging, and Monitoring of Chronic Hepatitis C - Hepatitis C Online
![Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir - ScienceDirect Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S134743672030361X-gr1.jpg)
Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir - ScienceDirect
![Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir | Scientific Reports Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-020-73641-9/MediaObjects/41598_2020_73641_Fig1_HTML.png)
Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir | Scientific Reports
![Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus. - Abstract - Europe PMC Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus. - Abstract - Europe PMC](https://europepmc.org/articles/PMC5923114/bin/zac0051870790001.jpg)
Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus. - Abstract - Europe PMC
![Ribavirin: pharmacology, multiple modes of action and possible future perspectives | Future Virology Ribavirin: pharmacology, multiple modes of action and possible future perspectives | Future Virology](https://www.futuremedicine.com/cms/10.2217/fvl-2018-0166/asset/images/medium/figure1.gif)
Ribavirin: pharmacology, multiple modes of action and possible future perspectives | Future Virology
![Sofosbuvir metabolism. The drug is phosphorylated to its active form in... | Download Scientific Diagram Sofosbuvir metabolism. The drug is phosphorylated to its active form in... | Download Scientific Diagram](https://www.researchgate.net/publication/268690153/figure/fig1/AS:295419885178886@1447444997697/Sofosbuvir-metabolism-The-drug-is-phosphorylated-to-its-active-form-in-the-hepatocytes.png)
Sofosbuvir metabolism. The drug is phosphorylated to its active form in... | Download Scientific Diagram
![Frontiers | Mechanism of Action of Small-Molecule Agents in Ongoing Clinical Trials for SARS-CoV-2: A Review Frontiers | Mechanism of Action of Small-Molecule Agents in Ongoing Clinical Trials for SARS-CoV-2: A Review](https://www.frontiersin.org/files/MyHome%20Article%20Library/840639/840639_Thumb_400.jpg)
Frontiers | Mechanism of Action of Small-Molecule Agents in Ongoing Clinical Trials for SARS-CoV-2: A Review
![Biology | Free Full-Text | The Metabolic Activation of Sofosbuvir Is Impaired in an Experimental Model of NAFLD Biology | Free Full-Text | The Metabolic Activation of Sofosbuvir Is Impaired in an Experimental Model of NAFLD](https://pub.mdpi-res.com/biology/biology-11-00693/article_deploy/html/images/biology-11-00693-g001.png?1651316340)
Biology | Free Full-Text | The Metabolic Activation of Sofosbuvir Is Impaired in an Experimental Model of NAFLD
![Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol | Scientific Reports Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-022-13657-5/MediaObjects/41598_2022_13657_Fig1_HTML.png)
Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol | Scientific Reports
![Population Pharmacokinetics of Sofosbuvir and Its Major Metabolite (GS-331007) in Healthy and HCV-Infected Adult Subjects Population Pharmacokinetics of Sofosbuvir and Its Major Metabolite (GS-331007) in Healthy and HCV-Infected Adult Subjects](https://www.natap.org/2015/images/122115/122115-10/AASLD2.gif)